Benefits Of DIM Supplements For Women
DIM is a nutrient that has many benefits for women. For example, it helps regulate the level of estrogen in the body. Estrogen plays an important role in a woman’s health and an imbalance can lead to bloating, hair loss, depression, insomnia, and an irregular menstrual cycle. Women may have to take DIM supplements to restore proper estrogen levels.
Anti-Inflammatory
Taking DIM supplements can help reduce inflammation in the body. Its main function is to activate an enzyme called AMPK. This enzyme is involved in the regulation of energy. When activated, it can reduce the production of insulin and reduce the tendency of the body to store energy as fat.
Several studies have shown that DIM can reduce the level of inflammation. Its anti-inflammatory effects include inhibiting the production of cytokines that increase the risk of disease. In a study, DIM decreased the levels of IL-17 and other pro-inflammatory cytokines. It has also been shown that DIM has anti-microbial, antiviral, and anti-tumor properties.
In addition to inhibiting inflammatory factors, DIM blocks phosphorylation of the MAPK and mTOR pathways. These results support DIM’s potential as a treatment for RA. These findings are consistent with those of previous studies and indicate that DIM may have therapeutic benefits in RA.
In a study involving mice, DIM affected pathohistological features in knee joints. Photomicrographs of knee joint sections stained with H&E were shown in the right panel. Inflammation severity scores were also shown on the right panel. The results are shown as means + standard deviations (SD).
In animal studies, DIM supplements can prevent arthritis. In the AIA group, mice that had been administered DIM supplements showed less severe arthritis. The mice were analyzed every five days, and they were observed to have less joint swelling. The mice in the DIM-treated group showed a decrease in the mean diameter of the knee joints.
Anti-Tumor
DIM inhibits c-Met, a receptor for hepatocyte growth factor (HGF). By inhibiting c-Met, DIM prevents the progression of NASH in mice. In addition, it inhibits Akt, a signaling pathway that enables cancer cells to grow. These effects suggest that DIM is a potential therapeutic agent for cancer.
DIM also inhibits the formation of active estrogen hormones in the body. It also promotes the oxidation of estrone to 2-hydroxyestrone, which suppresses tumor growth. Furthermore, DIM prevents the growth of new blood vessels, which are necessary for tumor growth. Several studies have also shown that cruciferous vegetables reduce the incidence of liver cancer.
In addition, DIM supplementation increases estrogen metabolism and lowers levels of androgen-specific antigen (androgens). Some research suggests that DIM may be an effective chemo-preventive supplement against cancer. It has also been shown to have some clinical benefits in the treatment of cervical/prostate dysplasia, the human papoma virus, and warts.
Despite the promising results of these studies, the safety of DIM remains a concern. The lack of well-designed clinical trials has prevented a thorough understanding of the safety of the supplement. However, some side effects are not serious and can be managed by lifestyle changes. Patients should discuss any potential side effects with their doctors.
DIM supplementation is a potentially safe, cost-effective option for cancer patients. However, it is important to note that DIM may interfere with some medications, so doctors should be consulted before beginning DIM treatment.
